vendredi 20 mai 2011

Recently adopted names for antineoplastics


Name
Code name
Type
Target(s)




abexinostat
PCI-24781, S-78454, PCI-24781-01, S-78454-1, CRA-024781-HCl, CRA-024781-01
synthetic small molecule
Histone deacetylase(s)
alisertib
MLN-8237
synthetic small molecule
Aurora A kinase, Aurora B kinase
cabozantinib
XL-184, BMS-907351
synthetic small molecule
MET RET VEGFR1 VEGFR2 VEGFR3
calaspargase pegol (asparaginase)
EZN-2285
enzyme

crenolanib
ARO-002; CP-868,596
synthetic small molecule
PDGFR
dabrafenib
GSK-2118436A
synthetic small molecule
MEK
dalantercept
ACE-041
protein
TGF-beta family
delanzomib
CEP-18770, CT-47098, NPH-007098
synthetic small molecule
Proteasome
erismodegib
LDE-225
synthetic small molecule
Smoothened (SMO)
ficlatuzumab
SCH-900105, AV-299
monoclonal antibody
Hepatocyte growth factor
galeterone
TOK-001, VN-124
natural product-derived small molecule
Androgen receptor (AR)
macitentan
ACT-064992
synthetic small molecule
Endothelin receptor A, endothelin receptor B
rucaparib
AG-14699, AG-014699, PF-01367338, AG-14447
synthetic small molecule
Poly (ADP-ribose) polymerase (PARP)
sepantronium
YM-155
synthetic small molecule
BIRC5 baculoviral IAP repeat containing 5  (BIRC5)
sitaxentan
TBC-11251z, TBC-11251Na
synthetic small molecule
Endothelin receptor A, endothelin receptor B
trametinib
GSK-1120212
synthetic small molecule
MEK
volasertib
BI-6727
synthetic small molecule
Polo-like kinase 1 (PLK1)






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