First-in-class
cancer drug approved to fight melanoma
The US
Food and Drug Administration (FDA) has approved the first cancer drug to
inhibit a protein — called MEK — that acts in a pathway that fuels tumour
growth. The drug, called Mekinist (trametinib), was approved on 29 May for use
in advanced melanomas with specific mutations. Other MEK-targeting drugs are
being studied in a wide range of tumours, including lung and thyroid cancers.
By Heidi Ledford. In Nature.com (blog)
New
Possibilities for Prostate Cancer Treatment Revealed
Researchers
have identified a sub-group of cells that could contribute to prostate cancer
recurrence, opening up new ways to treat the disease, which claims more than 3000
lives a year in Australia .
In Science
Daily
Barbara
Brenner, breast cancer awareness advocate, dies at 61
Barbara
Brenner, who directed Breast Cancer Action, a San Francisco-based breast cancer
awareness group, for 15 years, died May 10 at her home in San Francisco . She was 61. Although she “beat
the breast cancer odds,” as she once said, Ms. Brenner resigned her post in
2010 because of amyotrophic lateral sclerosis, a degenerative nerve disorder
known as ALS.
By Valerie J. Nelson. In Washington Post
http://www.washingtonpost.com/local/obituaries/barbara-brenner-breast-cancer-awareness-advocate-dies-at-61/2013/05/29/6ae7758e-c7d5-11e2-8da7-d274bc611a47_story.html
Immunotherapy's
cancer remit widens
Combination
therapies hold great promise, but at what cost?
By Heidi Ledford. In Nature.com (blog)
Cancer de la prostate : le Jevtana
bientôt remboursé
Marisol Touraine, la ministre de la
santé, a annoncé, vendredi 31 mai, le remboursement en France du Jevtana, un
traitement coûteux du groupe Sanofi contre le cancer de la prostate.
Interpellée par l'Association nationale des malades du cancer de la prostate
(Anamacap), Mme Touraine a indiqué sur France Info que le médicament serait
pris en charge par l'assurance-maladie.
Dans Le Monde
Deux nouvelles thérapies ciblées du
mélanome métastatique inopérable ainsi qu'un test diagnostic pour identifier le
bon traitement ont reçu une autorisation de mise sur le marché (AMM) de la Food and Drug Administration
(FDA). Les nouveaux agents, le dabrafenib (Tafinalar®) et le trametinib
(Mekinist®), ont été développés par GlaxoSmithKline. Tous deux sont des
traitements oraux mais ont des mécanismes d'action légèrement différents.
Par Zosia
Chustecka, Aude Lecrubier. Dans Medscape
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