vendredi 28 décembre 2012

Press Review (December 29, 2012) – Revue de presse (29 décembre 2012)

Elwood V. Jensen, Pioneer in Breast Cancer Treatment, Dies at 92
Elwood V. Jensen, a medical researcher whose studies of steroid hormones led to new treatments for breast cancer that have been credited with saving or extending hundreds of thousands of lives, died on Dec. 16 in Cincinnati. He was 92.
By Daniel E. Slotnik. In The New York Times

US cancer screening rates decline over the last 10 years, finds new study
The rate of people who seek preventive cancer screenings has fallen over the last ten years in the United States with wide variations between white-collar and blue-collar workers, according to a University of Miami Miller School of Medicine study published on December 27 in the open-access journal Frontiers in Cancer Epidemiology.
In EurekAlert (press release)

Anti-Androgen Therapies to Prevent Prostate Cancer Are Not One Size Fits All
A new study suggests that chemoprevention with anti-androgen therapies may not benefit all patients at risk for prostate cancer and could cause harm to some. Researchers at the Dana-Farber Cancer Institute and Harvard Medical School have identified a genetic mutation that actually results in a more robust transition from a precancerous to cancerous state when exposed to androgen deprivation.
By Anna Azvolinsky. In Cancer Network

Ability to Metabolize Tamoxifen Affects Breast Cancer Outcomes
For nearly a decade, breast cancer researchers studying the hormone therapy tamoxifen have been divided as to whether genetic differences in a liver enzyme affect the drug's effectiveness and the likelihood breast cancer will recur. A new study by researchers from the Mayo Clinic Cancer Center and the Austrian Breast and Colorectal Cancer Study Group provides evidence that genetic differences in the enzyme CYP2D6 play a key role in how well tamoxifen work.
In Science Daily (press release)

Breast cancer cells interact with non-cancerous tissue to drive metastasis
In addition to mutations, environmental conditions created by the tissues surrounding tumors (stroma) play a major role in cancer progression. Researchers led by Gregg Semenza at Johns Hopkins University examined the interactions between breast cancer cells and the stroma to identify underlying pro-metastatic molecular mechanisms.
In Science Codex

NIH study suggests gene variation may shape bladder cancer treatment
Patients who have inherited a specific common genetic variant develop bladder cancer tumors that strongly express a protein known as prostate stem cell antigen (PSCA), which is also expressed in many pancreatic and prostate tumors, according to research at the National Institutes of Health.
In National Institutes of Health (press release)

Cyclin D1b is a genetic reprogrammer that drives cancer progression
Researchers led by Karen Knudsen at Thomas Jefferson University's Kimmel Cancer Center examined the role of cyclin D1b in prostate cancer.
In Science Codex

Bowel cancer gene discovery cracks mystery of families with a strong history of the disease
Cancer Research UK-funded scientists have discovered that two gene faults increase the risk of bowel cancer in families with a strong history of developing the disease, who, until now, had no explanation as to why their risk was greater. The research is published in Nature Genetics.
In Cancer Research UK

What Is a Meaningful Increased Survival?
In their quest for new agents, pharmaceutical researchers test millions of substances all over the world. They like using color-forming reactions to identify new molecules. However, in intensively colored solutions or in the case of mixtures with multiple substances these tests fail. As part of his doctoral thesis, Martin Stein, member of staff at the Chair of Biochemistry at the Technische Universitaet Muenchen, developed a testing reaction based on magnetic resonance data. It helps find a specific pharmaceutical molecule among hundreds of different substances even in the most turbid of bacterial brews
By Rebecca Bechhold. In Cancer Network (blog)

Découverte de deux gênes responsables du cancer de l'intestin
Des chercheurs britanniques pensent avoir trouvé pourquoi certaines familles sont très exposées au cancer de l’intestin. Deux gênes, transmis par les parents aux enfants, seraient en effet responsables de l’augmentation du risque de formation d'une tumeur.
Dans JOL Press

Cancer de la prostate: Un virus caché dans un macrophage pour tuer la tumeur
C’est à nouveau l’approche par virus oncolytique, un virus capable d’infecter uniquement les cellules cancéreuses et de les détruire, qui vient d’être testée pour le traitement du cancer avancé de la prostate chez l'homme.
Dans Santé.log

Le dépistage du cancer du col de l'utérus gratuit dès le 1er janvier
Le dépistage du cancer du col de l'utérus sera gratuit dans quelques jours. Les frottis (qui coûtent aujourd'hui 13 euros aux patientes) seront intégralement remboursés. C'est l'une des décisions prises vendredi soir lors du dernier Conseil des ministres de l'année.
Sur RTBF  

La cigarette affecterait les gènes du cancer‎
Le fait de fumer des cigarettes pourrait affecter les gènes du cancer dans l’ADN, montrant que la consommation de tabac altèrerait chimiquement l’activité des gènes faisant augmenter le risque de cancer.
Par Sandra Besson. Dans Actualités News Environnement

Cancer du sein en Algérie : 3 000 décès d'Algériennes par an
Environ 9 000 nouveaux cas de cancer du sein sont découverts chaque année en Algérie, et plus de 3000 victimes en meurent.
Par J Boukraa. Dans

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