mardi 27 décembre 2011

Recently adopted names for antitumoral compounds (2011) - Noms d’antitumoraux adoptés récemment (2011)


Name
Code name
Type
Target(s)




abexinostat
PCI-24781, S-78454, PCI-24781-01, S-78454-1, CRA-024781-HCl, CRA-024781-01
synthetic small molecule (petite molecule synthétique)
Histone deacetylase(s)
alisertib
MLN-8237
synthetic small molecule (petite molecule synthétique)
Aurora A kinase, Aurora B kinase
XAN-02, AS-1413
synthetic small molecule (petite molecule synthétique)
DNA intercalator
XL-184, BMS-907351
synthetic small molecule (petite molecule synthétique)
MET RET VEGFR1 VEGFR2 VEGFR3
calaspargase pegol (asparaginase)
EZN-2285
enzyme

ARO-002; CP-868,596
synthetic small molecule (petite molecule synthétique)
PDGFR
crenolanib besylate
ARO-002-26; CP-868,596-26
synthetic small molecule (petite molecule synthétique)
PDGFRA
PDGFRB
dabrafenib
GSK-2118436A
synthetic small molecule (petite molecule synthétique)
MEK
dalantercept
ACE-041
Protein (protéine)
TGF-beta family
delanzomib
CEP-18770, CT-47098, NPH-007098
synthetic small molecule (petite molecule synthétique)
Proteasome
 BMS-901608
HuLuc63
antibody (anticorps)
 SLAM family member 7 (CD2-like receptor activating cytotoxic cells, CD319 antigen), CS1
erismodegib
LDE-225
synthetic small molecule (petite molecule synthétique)
Smoothened (SMO)
SCH-900105, AV-299
monoclonal antibody (anticorps monoclonal)
Hepatocyte growth factor
IMC-20DS7
monoclonal antibody
(anticorps monoclonal)
gp75 (melanoma)
TOK-001, VN-124
natural product-derived small molecule (petite molécule dérivée)
Androgen receptor (AR)
ganetespib
STA-9090
synthetic small molecule (petite molecule synthétique)
Hsp90
ixazomib
MLN2238
synthetic small molecule (petite molecule synthétique)
20S proteasome b5 site
macitentan
ACT-064992
synthetic small molecule
Endothelin receptor A, endothelin receptor B
niraparib
MK4827 or MK-4827
synthetic small molecule (petite molecule synthétique)
Poly(ADP-ribose) polymerase (PARP)
TAK-700
synthetic small molecule (petite molecule synthétique)
steroid 17,20 lyase (prostate cancer)
LBH589
synthetic small molecule (petite molecule synthétique)
Histone déacétylases
BAY 73-4506
synthetic small molecule (petite molecule synthétique)
KIT, PDGFR, RAF,,RET
rigosertib sodium
ON 01910.Na
Estybon
synthetic small molecule (petite molecule synthétique)
Polo-like kinase
AG-14699, AG-014699, PF-01367338, AG-14447
synthetic small molecule (petite molecule synthétique)
Poly (ADP-ribose) polymerase (PARP)
sepantronium
YM-155
synthetic small molecule (petite molecule synthétique)
BIRC5 baculoviral IAP repeat containing 5  (BIRC5)
TBC-11251z, TBC-11251Na
synthetic small molecule (petite molecule synthétique)
Endothelin receptor A, endothelin receptor B
tivantinib
ARQ 197
synthetic small molecule (petite molecule synthétique)
c-MET receptor tyrosine kinase
trametinib
GSK-1120212
synthetic small molecule (petite molecule synthétique)
MEK
trebananib
AMG-386
Antibody derived (dérivé d’anticorps)
angiopoietin1/2
BI-6727
synthetic small molecule (petite molecule synthétique)
Polo-like kinase 1 (PLK1)






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